Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 20/20 | 0.80 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.80 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13942020 | 0.90 | PTGER4 (0.83) | PTGER4CYP1A2CYP2D6 | |
| SCHEMBL3557529 | 0.89 | PTGER4 (1.00) | PTGER4CYP1A2CYP2D6 | |
| SCHEMBL4037304 | 0.86 | PTGER4 (0.62) | PTGER4CYP1A2CYP2D6 | |
| SCHEMBL3557608 | 0.85 | PTGER4 (0.91) | PTGER4CYP1A2CYP2D6 | |
| SCHEMBL3963667 | 0.84 | PTGER4 (0.89) | PTGER4CYP1A2CYP2D6 | |
| SCHEMBL13942573 | 0.84 | PTGER4 (0.89) | PTGER4CYP1A2CYP2D6 | |
| SCHEMBL4410607 | 0.84 | PTGER4 (0.89) | PTGER4CYP1A2CYP2D6 | |
| SCHEMBL3566760 | 0.84 | PTGER4 (0.89) | PTGER4CYP1A2CYP2D6 | |
| SCHEMBL3963663 | 0.83 | PTGER4 (0.87) | PTGER4CYP1A2CYP2D6 | |
| SCHEMBL3561110 | 0.82 | PTGER4 (0.85) | PTGER4CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009019281-A1 | BENZOISOINDOLE DERIVATIVES AND THEIR USE AS EP4 RECEPTOR AGONISTS FOR THE TREATMENT OF PAIN | GLAXO GROUP LIMITED (GB) | 2009-02-12 | — | — | WO | claimed |
| WO-2009019281-A1 | BENZOISOINDOLE DERIVATIVES AND THEIR USE AS EP4 RECEPTOR AGONISTS FOR THE TREATMENT OF PAIN | GLAXO GROUP LIMITED (GB) | 2009-02-12 | — | — | WO | disclosed |
| WO-2009019281-A1 | BENZOISOINDOLE DERIVATIVES AND THEIR USE AS EP4 RECEPTOR AGONISTS FOR THE TREATMENT OF PAIN | GLAXO GROUP LIMITED (GB) | 2009-02-12 | — | — | WO | disclosed |