Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.51 |
| ▸ | PPARA | Q07869 | 16/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4025387 | 0.91 | PPARG (0.57) | PPARGPPARA | |
| SCHEMBL4026013 | 0.89 | FFAR1 (0.54) | PPARGPPARAFFAR1KDRMAPT | |
| SCHEMBL4026911 | 0.88 | FFAR1 (0.56) | PPARGPPARAFFAR1KDRMAPT | |
| SCHEMBL4027562 | 0.87 | FFAR1 (0.53) | PPARGPPARAFFAR1KDRMAPT | |
| SCHEMBL4028565 | 0.87 | FFAR1 (0.53) | PPARGPPARAFFAR1KDRMAPT | |
| SCHEMBL4030774 | 0.86 | FFAR1 (0.52) | PPARGPPARAFFAR1KDR | |
| SCHEMBL4025977 | 0.85 | PPARA (0.52) | PPARGPPARAFFAR1KDRMAPT | |
| SCHEMBL4028342 | 0.85 | PPARA (0.51) | PPARGPPARAFFAR1KDRMAPT | |
| SCHEMBL4031222 | 0.85 | FFAR1 (0.50) | PPARGPPARAFFAR1KDRMAPT | |
| SCHEMBL4025872 | 0.85 | FFAR1 (0.50) | PPARGPPARAFFAR1KDRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569916-B1 | SUBSTITUTED ARALKYL DERIVATIVES | CADILA HEALTHCARE LTD (IN) | 2009-01-07 | — | — | EP | claimed |