Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.61 |
| ▸ | PPARG | P37231 | 16/20 | 0.55 |
| ▸ | PPARA | Q07869 | 16/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4035539 | 0.92 | FFAR1 (0.56) | FFAR1PPARGPPARAKDRMAPT | |
| SCHEMBL4031396 | 0.92 | FFAR1 (0.64) | FFAR1PPARGPPARAKDRKDM4E | |
| SCHEMBL2534811 | 0.91 | FFAR1 (0.63) | FFAR1PPARGPPARAKDRKDM4E | |
| SCHEMBL4030062 | 0.91 | FFAR1 (0.63) | FFAR1PPARGPPARAKDRKDM4E | |
| SCHEMBL4032405 | 0.91 | FFAR1 (0.63) | FFAR1PPARGPPARAKDRKDM4E | |
| SCHEMBL4034488 | 0.90 | FFAR1 (0.62) | FFAR1PPARGPPARAKDRKDM4E | |
| SCHEMBL5202665 | 0.89 | FFAR1 (0.61) | FFAR1PPARGPPARAKDRKDM4E | |
| SCHEMBL4032841 | 0.89 | FFAR1 (0.61) | FFAR1PPARGPPARAKDRKDM4E | |
| SCHEMBL4034630 | 0.89 | FFAR1 (0.68) | FFAR1PPARGPPARAKDRKDM4E | |
| SCHEMBL4037966 | 0.89 | FFAR1 (0.63) | FFAR1PPARGPPARAKDRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1357115-B1 | ALKANOIC ACID DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2009-06-17 | — | — | EP | disclosed |
| US-7238716-B2 | Alkanoic acid derivatives process for their production and use thereof | TAKEDA PHARMACEUTICALS COMPANY LIMITED (JP) | 2007-07-03 | — | — | US | disclosed |
| EP-1357115-A1 | ALKANOIC ACID DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2003-10-29 | — | — | EP | disclosed |