SCHEMBL4032228

SCHEMBL4032228

CCC(C)OC(Cc1ccc(OCCc2nc(-c3ccc(Cl)s3)oc2C)cc1)C(=O)O

nearest known ligand 0.70

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARG P37231 19/20 0.70
PPARA Q07869 16/20 0.64
PPARD Q03181 3/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4034246 0.93 PPARG (0.80) PPARGPPARAPPARD
SCHEMBL4034968 0.92 PPARG (0.63) PPARGPPARAPPARD
SCHEMBL4028696 0.90 PPARG (0.70) PPARGPPARAPPARD
SCHEMBL4030504 0.89 PPARG (0.80) PPARGPPARAPPARD
SCHEMBL4027534 0.89 PPARG (0.85) PPARGPPARAPPARD
SCHEMBL4034275 0.86 PPARG (0.80) PPARGPPARAPPARD
SCHEMBL4029552 0.85 PPARG (0.68) PPARGPPARAPPARD
SCHEMBL4026126 0.84 PPARG (0.76) PPARGPPARAPPARD
SCHEMBL4201143 0.83 PPARG (0.75) PPARGPPARAPPARD
SCHEMBL4025371 0.83 PPARG (1.00) PPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1569916-B1 SUBSTITUTED ARALKYL DERIVATIVES CADILA HEALTHCARE LTD (IN) 2009-01-07 EP claimed