⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11985893 | 0.75 | — | — | |
| SCHEMBL1128280 | 0.75 | — | — | |
| SCHEMBL30105439 | 0.75 | — | — | |
| SCHEMBL30982621 | 0.75 | — | — | |
| SCHEMBL3190050 | 0.75 | — | — | |
| SCHEMBL25261269 | 0.71 | — | — | |
| SCHEMBL1850861 | 0.71 | — | — | |
| SCHEMBL25037223 | 0.71 | — | — | |
| SCHEMBL21806962 | 0.71 | — | — | |
| SCHEMBL24553668 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024079623-A1 | TRICYCLIC COMPOUNDS AND THEIR USES | NOVARTIS AG (CH) | 2024-04-18 | — | — | WO | disclosed |
| EP-1539151-B1 | BIARYL COMPOUNDS HAVING ANTI-INFECTIVE ACTIVITY | GENESOFT PHARMACEUTICALS INC (US) | 2009-03-18 | — | — | EP | disclosed |
| US-7498349-B2 | Biaryl compounds having anti-infective activity | GENESOFT PHARMACEUTICALS, INC. (US) | 2009-03-03 | — | — | US | disclosed |
| EP-1539151-A4 | BIARYL COMPOUNDS HAVING ANTI-INFECTIVE ACTIVITY | GENESOFT PHARMACEUTICALS INC (US) | 2006-10-11 | — | — | EP | disclosed |
| US-20060128747-A1 | Biaryl compounds having anti-infective activity | GENESOFT PHARMACEUTICALS,INC. (US) | 2006-06-15 | — | — | US | disclosed |
| EP-1539151-A1 | BIARYL COMPOUNDS HAVING ANTI-INFECTIVE ACTIVITY | Genesoft Pharmaceuticals, Inc. (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004012736-A1 | BIARYL COMPOUNDS HAVING ANTI-INFECTIVE ACTIVITY | GENESOFT PHARMACEUTICALS, INC. (US) | 2004-02-12 | — | — | WO | disclosed |