Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 20/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4031867 | 0.88 | BDKRB1 (1.00) | BDKRB1 | |
| SCHEMBL4036439 | 0.85 | BDKRB1 (0.81) | BDKRB1 | |
| SCHEMBL5420078 | 0.83 | BDKRB1 (1.00) | BDKRB1 | |
| SCHEMBL4037306 | 0.83 | BDKRB1 (0.79) | BDKRB1 | |
| SCHEMBL10181571 | 0.82 | BDKRB1 (1.00) | BDKRB1 | |
| SCHEMBL10182469 | 0.81 | BDKRB1 (1.00) | BDKRB1 | |
| SCHEMBL10183440 | 0.80 | BDKRB1 (1.00) | BDKRB1 | |
| SCHEMBL9947842 | 0.80 | BDKRB1 (0.70) | BDKRB1 | |
| SCHEMBL10180391 | 0.79 | BDKRB1 (1.00) | BDKRB1 | |
| SCHEMBL10182433 | 0.79 | BDKRB1 (1.00) | BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1723143-B1 | AMINO CYCLOPROPANE CARBOXAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | MERCK & CO INC (US) | 2009-02-18 | — | — | EP | disclosed |
| EP-1723143-B1 | AMINO CYCLOPROPANE CARBOXAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | MERCK & CO INC (US) | 2009-02-18 | — | — | EP | disclosed |
| US-20070189865-A1 | Amino cyclopropane carboxamide derivatives as bradykinin antagonists | MERCK & CO., INC. | 2007-08-16 | — | — | US | disclosed |
| US-20070189865-A1 | Amino cyclopropane carboxamide derivatives as bradykinin antagonists | MERCK & CO., INC. | 2007-08-16 | — | — | US | disclosed |
| US-20070189865-A1 | Amino cyclopropane carboxamide derivatives as bradykinin antagonists | MERCK & CO., INC. | 2007-08-16 | — | — | US | disclosed |