⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12384189 | 0.74 | — | — | |
| SCHEMBL166196 | 0.71 | — | — | |
| SCHEMBL166194 | 0.71 | — | — | |
| SCHEMBL75894 | 0.71 | — | — | |
| SCHEMBL11248990 | 0.69 | — | — | |
| SCHEMBL4915538 | 0.67 | — | — | |
| SCHEMBL12733368 | 0.67 | — | — | |
| SCHEMBL790570 | 0.63 | — | — | |
| SCHEMBL10714020 | 0.62 | — | — | |
| SCHEMBL9683666 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3146977-B1 | TFPI INHIBITORS AND METHODS OF USE | TAKEDA PHARMACEUTICALS CO (JP) | 2024-05-08 | — | — | EP | disclosed |
| CN-115232086-B | Preparation method of 4-benzyl-2 (3H) -oxazolone | 扬州市普林斯医药科技有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-115010677-B | Preparation method of 4-phenyl-2 (3H) -oxazolone | 扬州市普林斯医药科技有限公司 | 2024-05-03 | — | — | CN | disclosed |
| US-11793855-B2 | TFPI inhibitors and methods of use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-10-24 | — | — | US | disclosed |
| CN-115232086-A | Preparation method of 4-benzyl-2 (3H) -oxazolone | 扬州市普林斯医药科技有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-115010677-A | Preparation method of 4-phenyl-2 (3H) -oxazolone | 扬州市普林斯医药科技有限公司 | 2022-09-06 | — | — | CN | disclosed |
| US-8389442-B2 | N-phenyl-′(4-pyridyl)-azinyl!amine derivatives as plant protection agents | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-05 | — | — | US | disclosed |
| US-20110082134-A1 | 1,2,3-Trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia | ARENA PHARMACEUTICALS, INC. (US) | 2011-04-07 | — | — | US | disclosed |
| EP-1613156-B1 | N-PHENYL- \" (4-PYRIDYL)- AZINYL]AMINE DERIVATIVES AS PLANT PROTECTION AGENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-05-06 | — | — | EP | disclosed |
| US-20070032490-A1 | N-Phenyl-'(4-pyridyl)-azinyl!amine derivatives as plant protection agents | SYNGENTA CROP PROTECTION, INC. | 2007-02-08 | — | — | US | disclosed |
| CN-1136202-C | CO2 and propiolic reaction process of preparing 5-methylene-2-oxazolidone compounds | 中国科学院上海有机化学研究所 | 2004-01-28 | — | — | CN | disclosed |
| CN-1136202-C | CO2 and propiolic reaction process of preparing 5-methylene-2-oxazolidone compounds | 中国科学院上海有机化学研究所 | 2004-01-28 | — | — | CN | disclosed |
| CN-1323790-A | CO2 and propiolic reaction process of preparing 5-methylene-2-oxazolidone compounds | SHANGHAI INST ORGANIC CHEM (CN) | 2001-11-28 | — | — | CN | disclosed |
| CN-1323790-A | CO2 and propiolic reaction process of preparing 5-methylene-2-oxazolidone compounds | SHANGHAI INST ORGANIC CHEM (CN) | 2001-11-28 | — | — | CN | disclosed |