SCHEMBL403341

SCHEMBL403341

COCCOC(=O)/C=C\C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 10/20 0.67
ATM Q13315 1/20 0.48
TSHR P16473 3/20 0.39
TP53 P04637 1/20 0.39
EGLN1 Q9GZT9 1/20 0.39
EGLN3 Q9H6Z9 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MAPT P10636 2/20 0.39
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
KEAP1 Q14145 1/20 0.39
NFE2L2 Q16236 1/20 0.39
RAB9A P51151 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2890671 1.00 HCAR2 (0.67) HCAR2ATMTSHRTP53EGLN1
SCHEMBL403342 1.00 HCAR2 (0.67) HCAR2ATMTSHRTP53EGLN1
SCHEMBL3800597 0.98 HCAR2 (0.64) HCAR2ATMTSHRTP53EGLN1
Ammonia Solution, Strong SCHEMBL27753065 0.98 HCAR2 (0.64) HCAR2ATMTSHRTP53EGLN1
SCHEMBL8901889 0.94 HCAR2 (0.60) HCAR2ATMTSHRTP53SMN1; SMN2
SCHEMBL30298850 0.94 HCAR2 (0.60) HCAR2ATMTSHRTP53SMN1; SMN2
SCHEMBL19048762 0.94 HCAR2 (0.60) HCAR2ATMTSHRTP53SMN1; SMN2
SCHEMBL1264625 0.94 HCAR2 (0.60) HCAR2ATMTSHRTP53SMN1; SMN2
SCHEMBL1264623 0.94 HCAR2 (0.60) HCAR2ATMTSHRTP53SMN1; SMN2
SCHEMBL403340 0.91 ATM (0.56) HCAR2ATMTSHRTP53SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114292588-B High-abrasion organic silicon coating and preparation method and application thereof 东莞市贝特利新材料有限公司 2022-08-23 CN claimed
CN-114292588-A High-abrasion organic silicon coating and preparation method and application thereof 东莞市贝特利新材料有限公司 2022-04-08 CN claimed
CN-108478363-B A kind of dedicated urine sampler of male patient 徐州腾睿智能装备有限公司 2019-11-12 CN claimed
CN-108309637-B A kind of simple urine collecting device of male patient 徐州市康复医院 2019-11-12 CN claimed
CN-108478363-A A kind of special urine sampler of male patient 徐州市康复医院 2018-09-04 CN claimed
CN-108309637-A A kind of simple urine collecting device of male patient 徐州市康复医院 2018-07-24 CN claimed
CN-106398227-A A silicone composition, a preparing method thereof and uses of the composition 天津凯华绝缘材料股份有限公司 2017-02-15 CN claimed
CN-106189258-A Adjustable silicon composition of curing rate and its preparation method and application 天津凯华绝缘材料股份有限公司 2016-12-07 CN claimed
US-4904736-A Acrylic rubber composition DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1990-02-27 US claimed
EP-0115081-B1 ELASTOMER ACRYLIC ESTER TYPE COPOLYMER DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1989-04-26 EP claimed
EP-0140530-B1 LATENTLY-CURABLE ORGANOSILICONE RELEASE COATING COMPOSITION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-03-08 EP claimed
EP-0140530-A1 Latently-curable organosilicone release coating composition MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-05-08 EP claimed
US-4508885-A VULCANIZED AND MOLDED YO A RUBBER COMPOUND DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1985-04-02 US claimed
US-4504645-A GELATION INHIBITION USING A MONOESTER OR -AMIDE OF AN UNSATURATED DICARBOXYLIC ACID; SHELF LIFE; HEAT CURING MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-03-12 US claimed
EP-0115081-A2 Elastomer acrylic ester type copolymer DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1984-08-08 EP claimed
CN-117265895-A Solvent-free environment-friendly low-viscosity high-performance printing silica gel and preparation method thereof 广东聚思新材料科技有限公司 2023-12-22 CN disclosed
US-11591426-B2 Copolymer, wetting agent, medical device, and method for producing same TORAY INDUSTRIES, INC. (JP) 2023-02-28 US disclosed
US-4101459-A TRIFLUOROMETHANESULFONIC ACID SALTS CIBA-GEIGY CORPORATION (US) 1978-07-18 US disclosed
US-4009684-A Water soluble polymers useful in the preparation of novel animal litter NATIONAL PATENT DEVELOPMENT CORPORATION (US) 1977-03-01 US disclosed
US-4003991-A WATER SOLUBLE ACRYLIC, 2-ALKENAMIDE, OR ETHYLENIMINE POLYMER; TOPICAL MEDICAMENTS NATIONAL PATENT DEVELOPMENT CORPORATION (US) 1977-01-18 US disclosed