SCHEMBL4033641

SCHEMBL4033641

[O]CC(Cl)(Cl)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22788 0.75
SCHEMBL23836 0.75
SCHEMBL3362643 0.74
SCHEMBL4093525 0.72
SCHEMBL10905075 0.72
SCHEMBL27224569 0.69
SCHEMBL4394690 0.67
SCHEMBL24965 0.65
SCHEMBL9055 0.65
SCHEMBL10418027 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE36617-E Anastrozole and salts as anticancer agent ZENECA LIMITED (GB) 2000-03-14 US claimed
EP-0296749-B1 (Substituted aralkyl) heterocyclic compounds ZENECA LTD (GB) 1994-10-26 EP claimed
US-4935437-A (Substituted aralkyl) heterocyclic compounds IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-06-19 US claimed
EP-0296749-A1 (Substituted aralkyl) heterocyclic compounds ZENECA LIMITED (GB) 1988-12-28 EP claimed
EP-0976737-B1 PYRAZOLE DERIVATIVES, PROCESS FOR PREPARING THE SAME, INTERMEDIATES, AND PEST CONTROL AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT NIHON NOHYAKU CO LTD (JP) 2009-06-10 EP disclosed
US-7371768-B2 Pyrazol derivatives, pest control agent comprising the same as active ingredient, and process for producing the same NIHON NOHYAKU CO., LTD. (JP) 2008-05-13 US disclosed
EP-1310497-B1 PYRAZOLE DERIVATIVE, PEST CONTROL AGENT COMPRISING THE SAME AS ACTIVE INGREDIENT AND PROCESS FOR PRODUCING THE SAME NIHON NOHYAKU CO LTD (JP) 2006-03-01 EP disclosed
US-20040053969-A1 Pyrazol derivatives, pest control agent comprising the same as active ingredient, and process for producing the same NIHON NOHYAKU CO., LTD. (JP) 2004-03-18 US disclosed
EP-1310497-A1 PYRAZOLE DERIVATIVES, PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT AND PROCESS FOR THEIR PRODUCTION Nihon Nohyaku Co., Ltd. (JP) 2003-05-14 EP disclosed
US-6335357-B1 1-ARYL-3-CYANO-5-(HET)ARYLALKYLAMINOPYRAZOLE DERIVATIVES; INSECTICIDES FOR AGRICULTURE AND HORTICULTURE MITSUBISHI CHEMICAL CORPORATION (JP) 2002-01-01 US disclosed
US-RE36617-E Anastrozole and salts as anticancer agent ZENECA LIMITED (GB) 2000-03-14 US disclosed
EP-0976737-A1 PYRAZOLE DERIVATIVES, PROCESS FOR PREPARING THE SAME, INTERMEDIATES, AND PEST CONTROL AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT MITSUBISHI CHEMICAL CORPORATION (JP) 2000-02-02 EP disclosed
EP-0726266-B1 Indazole compounds and the use thereof as fungicides, insecticides and miticides MITSUBISHI CHEM CORP (JP) 1998-01-07 EP disclosed
US-5705453-A INSECTICIDES, MITICIDES, FUNGICIDES MITSUBISHI CHEMICAL CORPORATION (JP) 1998-01-06 US disclosed
EP-0726266-A1 Indazole compounds and the use thereof as fungicides, insecticides and miticides MITSUBISHI CHEMICAL CORPORATION (JP) 1996-08-14 EP disclosed
EP-0296749-B1 (Substituted aralkyl) heterocyclic compounds ZENECA LTD (GB) 1994-10-26 EP disclosed
US-4968805-A Pyrazole derivatives and insecticidal fungicidal and miticidal compositions thereof MITSUBISHI KASEI CORPORATION (JP) 1990-11-06 US disclosed
US-4935437-A (Substituted aralkyl) heterocyclic compounds IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-06-19 US disclosed
EP-0329020-A1 Pyrazole derivatives, processes for their manufacture and insecticidal, miticidal and fungicidal compositions containg the derivatives as active ingredients MITSUBISHI KASEI CORPORATION (JP) 1989-08-23 EP disclosed
EP-0296749-A1 (Substituted aralkyl) heterocyclic compounds ZENECA LIMITED (GB) 1988-12-28 EP disclosed