Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 17/20 | 0.58 |
| ▸ | PDE4B | Q07343 | 16/20 | 0.58 |
| ▸ | PDE4A | P27815 | 15/20 | 0.58 |
| ▸ | PDE4C | Q08493 | 15/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4028104 | 0.93 | PDE4D (0.60) | PDE4DPDE4BPDE4APDE4CGFER | |
| SCHEMBL4027733 | 0.92 | PDE4D (0.62) | PDE4DPDE4BPDE4APDE4CGFER | |
| SCHEMBL4029599 | 0.89 | PDE4D (0.56) | PDE4DPDE4BPDE4APDE4CGFER | |
| SCHEMBL4027952 | 0.87 | PDE4D (0.56) | PDE4DPDE4BPDE4APDE4CGFER | |
| SCHEMBL4026196 | 0.87 | PDE4D (0.64) | PDE4DPDE4BPDE4APDE4CGFER | |
| SCHEMBL4027688 | 0.87 | PDE4D (0.58) | PDE4DPDE4BPDE4APDE4CGFER | |
| SCHEMBL4026328 | 0.87 | PDE4D (0.60) | PDE4DPDE4BPDE4APDE4CGFER | |
| SCHEMBL4029849 | 0.87 | PDE4D (0.60) | PDE4DPDE4BPDE4APDE4CGFER | |
| SCHEMBL4026016 | 0.86 | PDE4D (0.59) | PDE4DPDE4BPDE4APDE4CGFER | |
| SCHEMBL4028521 | 0.85 | PDE4D (0.62) | PDE4DPDE4BPDE4APDE4CGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620429-B1 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS SA (CH) | 2009-04-01 | — | — | EP | claimed |