Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 8/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | CYBB | P04839 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.41 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.41 |
| ▸ | MARK4 | Q96L34 | 9/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1926397 | 0.87 | NOX1 (0.37) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL1927571 | 0.87 | NOX1 (0.36) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL4033771 | 0.82 | GRM1 (0.46) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL4934512 | 0.82 | NOX1 (0.41) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL1926715 | 0.81 | NOX1 (0.43) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL1928027 | 0.79 | NOX1 (0.44) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL1929067 | 0.78 | NOX1 (0.43) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL1926490 | 0.78 | NOX1 (0.43) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL1926935 | 0.78 | NOX1 (0.43) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL1927695 | 0.77 | NOX1 (0.44) | NOX1MAPTGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675836-B1 | DERIVATIVES OF 4-PHENYLTHIAZOLES AND THE USE THEREOF AS MEDICAMENTS FOR TREATING NEURODEGENERATIVE DISEASES, PAIN AND EPILEPSY | IPSEN PHARMA (FR) | 2016-04-13 | — | — | EP | disclosed |
| EP-1379514-B1 | 5-MEMBERED HETEROCYCLES, PREPARATION AND APPLICATION THEREOF AS MEDICAMENTS | IPSEN PHARMA (FR) | 2009-07-15 | — | — | EP | disclosed |