Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.71 |
| ▸ | PPARG | P37231 | 18/20 | 0.59 |
| ▸ | PPARA | Q07869 | 15/20 | 0.59 |
| ▸ | PPARD | Q03181 | 2/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4031811 | 0.92 | FFAR1 (0.59) | FFAR1PPARGPPARAPPARDKDR | |
| SCHEMBL4035167 | 0.91 | FFAR1 (0.62) | FFAR1PPARGPPARAKDR | |
| SCHEMBL4033748 | 0.86 | FFAR1 (0.78) | FFAR1PPARGPPARAPPARDKDR | |
| SCHEMBL1745059 | 0.86 | FFAR1 (0.96) | FFAR1PPARGPPARAPPARD | |
| SCHEMBL4036976 | 0.84 | FFAR1 (0.52) | FFAR1PPARGPPARAKDR | |
| SCHEMBL4031905 | 0.83 | FFAR1 (0.70) | FFAR1PPARGPPARAPPARDKDR | |
| SCHEMBL4034348 | 0.82 | FFAR1 (0.71) | FFAR1PPARGPPARAPPARDKDR | |
| SCHEMBL4029056 | 0.82 | MAPT (0.57) | FFAR1PPARGPPARAKDR | |
| SCHEMBL4034751 | 0.81 | FFAR1 (0.81) | FFAR1PPARGPPARAPPARDKDR | |
| SCHEMBL4034630 | 0.81 | FFAR1 (0.68) | FFAR1PPARGPPARAKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1357115-B1 | ALKANOIC ACID DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2009-06-17 | — | — | EP | disclosed |
| US-7238716-B2 | Alkanoic acid derivatives process for their production and use thereof | TAKEDA PHARMACEUTICALS COMPANY LIMITED (JP) | 2007-07-03 | — | — | US | disclosed |
| EP-1357115-A1 | ALKANOIC ACID DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2003-10-29 | — | — | EP | disclosed |