⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8997376 | 0.71 | — | — | |
| SCHEMBL18926175 | 0.71 | — | — | |
| SCHEMBL14981542 | 0.71 | — | — | |
| SCHEMBL22094770 | 0.71 | — | — | |
| SCHEMBL6809738 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL18226426 | 0.69 | — | — | |
| SCHEMBL28769846 | 0.69 | — | — | |
| SCHEMBL1995001 | 0.69 | — | — | |
| SCHEMBL18926177 | 0.69 | — | — | |
| SCHEMBL16202682 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2033962-A1 | Tetracyclic indolopyridines as EG5 inhibitors | 4SC AG (DE) | 2009-03-11 | — | — | EP | claimed |
| EP-2033962-A1 | Tetracyclic indolopyridines as EG5 inhibitors | 4SC AG (DE) | 2009-03-11 | — | — | EP | disclosed |