Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4039987 | 0.92 | LCK (0.71) | LCKSRC | |
| SCHEMBL4036268 | 0.85 | LCK (0.61) | LCKSRC | |
| SCHEMBL7982128 | 0.81 | LCK (1.00) | LCK | |
| SCHEMBL4043066 | 0.81 | LCK (0.69) | LCKSRC | |
| SCHEMBL4039577 | 0.81 | LCK (0.64) | LCKSRC | |
| SCHEMBL4036151 | 0.81 | LCK (0.62) | LCKSRC | |
| SCHEMBL4040959 | 0.79 | LCK (0.69) | LCKSRC | |
| SCHEMBL4041705 | 0.79 | LCK (0.69) | LCKSRC | |
| SCHEMBL4036402 | 0.78 | LCK (0.67) | LCKSRC | |
| SCHEMBL4036450 | 0.78 | LCK (0.74) | LCKSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066286-B1 | HETEROCYCLO-SUBSTITUTED IMIDAZOPYRAZINE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2009-04-29 | — | — | EP | claimed |
| EP-1066286-B1 | HETEROCYCLO-SUBSTITUTED IMIDAZOPYRAZINE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2009-04-29 | — | — | EP | disclosed |