Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.37 |
| ▸ | TUBB | P07437 | 3/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4038387 | 0.87 | ERN1 (0.46) | ERN1KMT2ATUBB4ATUBBTUBA3C | |
| SCHEMBL15226057 | 0.86 | ERN1 (0.43) | ERN1KMT2ATUBB4ATUBBTUBA3C | |
| SCHEMBL4035765 | 0.86 | ERN1 (0.47) | ERN1KMT2ATUBB4ATUBBTUBA3C | |
| SCHEMBL4036647 | 0.85 | ERN1 (0.44) | ERN1KMT2ATUBB4ATUBBTUBA3C | |
| SCHEMBL4039533 | 0.85 | ERN1 (0.44) | ERN1KMT2ATUBB4ATUBBTUBA3C | |
| SCHEMBL15226080 | 0.82 | ERN1 (0.52) | ERN1TP53POLBKMT2ATUBB4A | |
| SCHEMBL15225776 | 0.80 | ERN1 (0.46) | ERN1TP53KMT2ATUBB4ATUBB | |
| SCHEMBL4036525 | 0.80 | ERN1 (0.55) | ERN1KMT2ATUBB4ATUBBTUBA3C | |
| SCHEMBL4043040 | 0.80 | ERN1 (0.49) | ERN1KMT2ATUBB4ATUBBTUBA3C | |
| SCHEMBL4037959 | 0.80 | ERN1 (0.49) | ERN1TP53KMT2ATUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066632-A1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | Chong Kun Dang Pharmaceutical Corp. (KR) | 2009-06-10 | — | — | EP | claimed |
| WO-2008038955-A1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2008-04-03 | — | — | WO | claimed |