Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 11/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | LOX | P28300 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13885796 | 0.85 | KDM4E (0.42) | KMT2AS1PR4ALDH1A1KDM4ENPC1 | |
| SCHEMBL23600775 | 0.83 | S1PR4 (0.57) | IDO1KMT2ATHRBS1PR4ALDH1A1 | |
| SCHEMBL29144991 | 0.81 | IDO1 (0.46) | IDO1KMT2ATHRBS1PR4ALDH1A1 | |
| SCHEMBL2434511 | 0.80 | S1PR4 (0.59) | IDO1KMT2ATHRBS1PR4ALDH1A1 | |
| SCHEMBL4757717 | 0.80 | S1PR4 (0.59) | IDO1KMT2ATHRBS1PR4ALDH1A1 | |
| SCHEMBL21605978 | 0.80 | S1PR4 (0.46) | IDO1KMT2ATHRBS1PR4NPC1 | |
| SCHEMBL7018653 | 0.77 | S1PR4 (0.52) | IDO1KMT2ATHRBS1PR4ALDH1A1 | |
| SCHEMBL6608419 | 0.74 | NQO2 (0.43) | ALDH1A1KDM4ENPC1RAB9ALMNA | |
| SCHEMBL7070645 | 0.71 | IDO1 (0.55) | IDO1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL13030470 | 0.69 | IDO1 (0.39) | IDO1KMT2AMEN1LOXAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066637-A1 | NOVEL SUBSTITUTED BIPYRIDINE DERIVATIVES AND THEIR USE AS ADENOSINE RECEPTOR LIGANDS | Bayer HealthCare AG (DE) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008028590-A1 | NOVEL SUBSTITUTED BIPYRIDINE DERIVATIVES AND THEIR USE AS ADENOSINE RECEPTOR LIGANDS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-03-13 | — | — | WO | disclosed |