Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | KIT | P10721 | 18/20 | 0.48 |
| ▸ | BRAF | P15056 | 18/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4041555 | 0.87 | F10 (0.45) | FLT1KDRKITBRAFF10 | |
| SCHEMBL4036764 | 0.85 | FLT1 (0.51) | FLT1KDRKITBRAF | |
| SCHEMBL3863944 | 0.84 | FLT1 (0.52) | FLT1KDRKITBRAFF10 | |
| SCHEMBL3869133 | 0.84 | KIT (0.59) | FLT1KDRKITBRAFF10 | |
| SCHEMBL2229333 | 0.84 | KDR (0.67) | FLT1KDRKITBRAFF10 | |
| SCHEMBL13772049 | 0.83 | KIT (0.50) | FLT1KDRKITBRAF | |
| SCHEMBL3873679 | 0.82 | KIT (0.61) | FLT1KDRKITBRAFF10 | |
| SCHEMBL4588770 | 0.82 | KIT (0.61) | FLT1KDRKITBRAFF10 | |
| SCHEMBL3867823 | 0.81 | KIT (0.51) | FLT1KDRKITBRAF | |
| SCHEMBL3865726 | 0.80 | KIT (0.51) | FLT1KDRKITBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392680-B1 | SELECTIVE ANTHRANILAMIDE PYRIDINE AMIDES AS INHIBITORS OF VEGFR-2 AND VEGFR-3 | BAYER SCHERING PHARMA AG (DE) | 2009-07-22 | — | — | EP | disclosed |