⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4039546 | 0.93 | — | — | |
| SCHEMBL5402386 | 0.89 | — | — | |
| SCHEMBL5393971 | 0.89 | — | — | |
| SCHEMBL5663356 | 0.88 | — | — | |
| SCHEMBL5661893 | 0.88 | — | — | |
| SCHEMBL5663043 | 0.88 | — | — | |
| SCHEMBL4041604 | 0.87 | — | — | |
| SCHEMBL5662492 | 0.86 | — | — | |
| SCHEMBL4040804 | 0.86 | — | — | |
| SCHEMBL5662496 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | disclosed |
| EP-1664052-B1 | FUSED HETEROCYCLES AS INHIBITORS OF GLUTAMATE RACEMASE (MURI) | ASTRAZENECA AB (SE) | 2009-02-18 | — | — | EP | disclosed |
| US-7371757-B2 | Fused heterocycles as inhibitors of glutamate racemase(MURI) | ASTRAZENECA AB (SE) | 2008-05-13 | — | — | US | disclosed |
| US-20070004761-A1 | Pyrazolo [3,4-d] pyrimidine derivatives and their use in the treatment of h.pylori infection | HETERO DRUGS LIMITED (IN) | 2007-01-04 | — | — | US | disclosed |
| EP-1585748-B1 | PYRAZOLO 3,4-d PYRIMIDINE DERIVATIVES AND THEIR USE I N THE TREATMENT OF H.PYLORI INFECTION | ASTRAZENECA AB (SE) | 2006-12-27 | — | — | EP | disclosed |
| US-20060252781-A1 | Fused heterocycles as inhibitors of glutamate racemase(muri) | ASTRAZENECA AB (SE) | 2006-11-09 | — | — | US | disclosed |
| US-20060100431-A1 | Biologically active compounds | AMURA THERAPEUTICS LIMITED (GB) | 2006-05-11 | — | — | US | disclosed |
| EP-1585748-A1 | PYRAZOLO 3,4-d PYRIMIDINE DERIVATIVES AND THEIR USE I N THE TREATMENT OF H.PYLORI INFECTION | AstraZeneca AB (SE) | 2005-10-19 | — | — | EP | disclosed |
| WO-2004056831-A1 | PYRAZOLO [3,4-d] PYRIMIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF H.PYLORI INFECTION | ASTRAZENECA AB (SE) | 2004-07-08 | — | — | WO | disclosed |