Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 15/20 | 0.57 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4042640 | 0.88 | ERN1 (0.49) | ERN1PIK3R1PIK3CAALDH1A1MAPT | |
| SCHEMBL4041509 | 0.81 | ERN1 (0.56) | ERN1PIK3R1PIK3CAPTPN2PTPN1 | |
| SCHEMBL15226080 | 0.80 | ERN1 (0.52) | ERN1PIK3R1PIK3CAALDH1A1MAPT | |
| SCHEMBL4036698 | 0.76 | ERN1 (0.68) | ERN1PIK3R1PIK3CAALDH1A1MAPT | |
| SCHEMBL4036525 | 0.75 | ERN1 (0.55) | ERN1PIK3R1PIK3CAALDH1A1MAPT | |
| SCHEMBL4040519 | 0.73 | ERN1 (0.47) | ERN1PIK3R1PIK3CAALDH1A1MAPT | |
| SCHEMBL12767031 | 0.73 | ERN1 (1.00) | ERN1 | |
| SCHEMBL4035385 | 0.72 | ERN1 (0.46) | ERN1PIK3R1PIK3CAALDH1A1MAPT | |
| SCHEMBL15225776 | 0.72 | ERN1 (0.46) | ERN1PIK3R1PIK3CAALDH1A1MAPT | |
| SCHEMBL4035765 | 0.72 | ERN1 (0.47) | ERN1PIK3R1PIK3CAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066632-A1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | Chong Kun Dang Pharmaceutical Corp. (KR) | 2009-06-10 | — | — | EP | claimed |
| WO-2008038955-A1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2008-04-03 | — | — | WO | claimed |