Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 17/20 | 0.66 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.56 |
| ▸ | NCS1 | P62166 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2430770 | 0.88 | CASR (0.69) | CASRCSNK1DNCS1 | |
| SCHEMBL2432067 | 0.88 | CASR (0.69) | CASRCSNK1DNCS1 | |
| SCHEMBL2432636 | 0.88 | CASR (0.64) | CASRCSNK1DNCS1 | |
| SCHEMBL14189788 | 0.88 | CASR (0.59) | CASRCSNK1DNCS1 | |
| SCHEMBL2429969 | 0.87 | CASR (0.68) | CASRCSNK1DNCS1 | |
| SCHEMBL4362893 | 0.87 | CASR (0.68) | CASRCSNK1DNCS1 | |
| SCHEMBL3644521 | 0.87 | CASR (0.68) | CASRCSNK1DNCS1 | |
| SCHEMBL2432280 | 0.87 | CASR (0.59) | CASRCSNK1DNCS1 | |
| SCHEMBL128460 | 0.86 | CASR (0.67) | CASRCSNK1DNCS1 | |
| SCHEMBL2431195 | 0.86 | CASR (0.62) | CASRCSNK1DNCS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2041103-A2 | DERIVATIVES OF UREA AND RELATED DIAMINES, METHODS FOR THEIR MANUFACTURE, AND USES THEREFOR | Galapagos SAS (FR) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008006625-A2 | DERIVATIVES OF UREA AND RELATED DIAMINES, METHODS FOR THEIR MANUFACTURE, AND USES THEREFOR | GALAPAGOS SAS (FR) | 2008-01-17 | — | — | WO | disclosed |