Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 13/20 | 0.43 |
| ▸ | PPARA | Q07869 | 13/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4034587 | 0.90 | KDR (0.51) | KDM4EFFAR1KDRPPARGPPARA | |
| SCHEMBL6998371 | 0.88 | KDM4E (0.53) | KDM4EFFAR1KDRPPARGPPARA | |
| SCHEMBL4034022 | 0.86 | KDR (0.42) | KDM4EFFAR1KDRPPARGPPARA | |
| SCHEMBL5403564 | 0.85 | KDM4E (0.47) | KDM4EFFAR1KDRPPARGPPARA | |
| SCHEMBL4030645 | 0.84 | FFAR1 (0.52) | KDM4EFFAR1PPARGPPARA | |
| SCHEMBL4035756 | 0.84 | PPARA (0.37) | KDM4EPPARGPPARAPPARD | |
| SCHEMBL4031015 | 0.84 | KDR (0.43) | KDM4EFFAR1KDRPPARGPPARA | |
| SCHEMBL4028802 | 0.83 | FFAR1 (0.64) | KDM4EFFAR1KDRPPARGPPARA | |
| SCHEMBL4035460 | 0.82 | FFAR1 (0.63) | KDM4EFFAR1KDRPPARGPPARA | |
| SCHEMBL4035103 | 0.82 | KDR (0.43) | KDM4EFFAR1KDRPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1357115-B1 | ALKANOIC ACID DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2009-06-17 | — | — | EP | disclosed |
| US-7238716-B2 | Alkanoic acid derivatives process for their production and use thereof | TAKEDA PHARMACEUTICALS COMPANY LIMITED (JP) | 2007-07-03 | — | — | US | disclosed |
| EP-1357115-A1 | ALKANOIC ACID DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2003-10-29 | — | — | EP | disclosed |