Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.71 |
| ▸ | EGFR | P00533 | 1/20 | 0.71 |
| ▸ | CSF1R | P07333 | 1/20 | 0.71 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.71 |
| ▸ | KIT | P10721 | 1/20 | 0.71 |
| ▸ | FLT1 | P17948 | 1/20 | 0.71 |
| ▸ | FLT4 | P35916 | 1/20 | 0.71 |
| ▸ | KDR | P35968 | 1/20 | 0.71 |
| ▸ | RXFP1 | Q9HBX9 | 19/20 | 0.70 |
| ▸ | RXFP2 | Q8WXD0 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5900627 | 0.90 | ABL1 (0.72) | ABL1EGFRCSF1RPDGFRBKIT | |
| SCHEMBL4038122 | 0.86 | FLT1 (0.75) | ABL1EGFRCSF1RPDGFRBKIT | |
| SCHEMBL2489551 | 0.86 | ABL1 (0.78) | ABL1EGFRCSF1RPDGFRBKIT | |
| SCHEMBL3865996 | 0.85 | ABL1 (0.76) | ABL1EGFRCSF1RPDGFRBKIT | |
| SCHEMBL3866257 | 0.85 | KIT (0.76) | ABL1EGFRCSF1RPDGFRBKIT | |
| SCHEMBL4976103 | 0.83 | KDR (1.00) | ABL1EGFRCSF1RPDGFRBKIT | |
| SCHEMBL29356168 | 0.83 | KDR (1.00) | ABL1EGFRCSF1RPDGFRBKIT | |
| SCHEMBL15528722 | 0.83 | RXFP1 (1.00) | ABL1EGFRCSF1RPDGFRBKIT | |
| SCHEMBL15529379 | 0.83 | RXFP1 (1.00) | ABL1EGFRCSF1RPDGFRBKIT | |
| SCHEMBL3865275 | 0.81 | RXFP1 (0.72) | ABL1EGFRCSF1RPDGFRBKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392680-B1 | SELECTIVE ANTHRANILAMIDE PYRIDINE AMIDES AS INHIBITORS OF VEGFR-2 AND VEGFR-3 | BAYER SCHERING PHARMA AG (DE) | 2009-07-22 | — | — | EP | disclosed |
| EP-1392680-A2 | SELECTIVE ANTHRANILAMIDE PYRIDINE AMIDES AS INHIBITORS OF VEGFR-2 AND VEGFR-3 | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002090352-A2 | SELECTIVE ANTHRANILAMIDE PYRIDINE AMIDES AS INHIBITORS OF VEGFR-2 AND VEGFR-3 | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-11-14 | — | — | WO | disclosed |