Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.36 |
| ▸ | TUBB | P07437 | 5/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.36 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.36 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4042642 | 0.93 | ERN1 (0.53) | ERN1MAPTALDH1A1TDP1TUBB4A | |
| SCHEMBL15226080 | 0.83 | ERN1 (0.52) | ERN1MAPTALDH1A1TSHRTUBB4A | |
| SCHEMBL15226057 | 0.82 | ERN1 (0.43) | ERN1MAPTALDH1A1TSHRTUBB4A | |
| SCHEMBL4035630 | 0.81 | ERN1 (0.62) | ERN1GABRA1GABRB2 | |
| SCHEMBL4036525 | 0.80 | ERN1 (0.55) | ERN1MAPTALDH1A1TSHRTUBB4A | |
| SCHEMBL4037959 | 0.80 | ERN1 (0.49) | ERN1MAPTALDH1A1TSHRTUBB4A | |
| SCHEMBL4043040 | 0.80 | ERN1 (0.49) | ERN1MAPTALDH1A1TSHRTUBB4A | |
| SCHEMBL4035765 | 0.78 | ERN1 (0.47) | ERN1MAPTALDH1A1TSHRTUBB4A | |
| SCHEMBL15225760 | 0.78 | ERN1 (0.48) | ERN1MAPTALDH1A1TDP1TSHR | |
| SCHEMBL15225990 | 0.78 | ERN1 (0.49) | ERN1MAPTALDH1A1TSHRTUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029572-A2 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007143597-A2 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2007-12-13 | — | — | WO | disclosed |