SCHEMBL403868

SCHEMBL403868

Cc1nc(Cl)ccc1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30503583 1.00
SCHEMBL1506533 0.79
SCHEMBL558598 0.79
SCHEMBL876343 0.78
SCHEMBL29427087 0.78
SCHEMBL1400779 0.78
SCHEMBL27474800 0.76
SCHEMBL247652 0.74
SCHEMBL21855865 0.74
SCHEMBL20844169 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1233672-A2 SYNERGISTIC HERBICIDAL ACTIVE SUBSTANCE COMBINATIONS Bayer Aktiengesellschaft (DE) 2002-08-28 EP claimed
EP-1221844-A2 SELECTIVE HERBICIDES BASED ON PYRIMIDINE-DERIVATIVES Bayer Aktiengesellschaft (DE) 2002-07-17 EP claimed
WO-2001035741-A2 SYNERGISTIC HERBICIDAL ACTIVE SUBSTANCE COMBINATIONS BAYER AKTIENGESELLSCHAFT (DE) 2001-05-25 WO claimed
WO-2001024633-A2 SELECTIVE HERBICIDES BASED ON PYRIMIDINE-DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 2001-04-12 WO claimed
EP-0046503-A1 Herbicidal agents on the the basis of cyclohexane-1,3-dione derivatives and 3,6-dichloro-2-picolinic-acid derivatives BASF Aktiengesellschaft (DE) 1982-03-03 EP claimed
JP-1090172-A None JP disclosed
US-20250340557-A1 PYRIMIDINE DERIVATIVE ASKA PHARMACEUTICAL CO., LTD. (JP) 2025-11-06 US disclosed
EP-4553068-A1 PYRIMIDINE DERIVATIVES ASKA Pharmaceutical Co., Ltd. (JP) 2025-05-14 EP disclosed
EP-4217062-B1 CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2024-10-09 EP disclosed
US-20240208902-A1 CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2024-06-27 US disclosed
EP-4010076-B1 (HETERO)ARYL-METHYL-THIO-BETA-D-GALACTOPYRANOSIDE DERIVATIVES IDORSIA PHARMACEUTICALS LTD (CH) 2024-01-17 EP disclosed
WO-2024010015-A1 PYRIMIDINE DERIVATIVES あすか製薬株式会社 2024-01-11 WO disclosed
US-5106984-A Reacting acrylonitrile and a dichloromethyl hydrocarbyl ketone, acidifying intermediate formed THE DOW CHEMICAL COMPANY (US) 1992-04-21 US disclosed
US-5084576-A Herbicides and nitrification inhibitors THE DOW CHEMICAL COMPANY (US) 1992-01-28 US disclosed
US-5084576-A Herbicides and nitrification inhibitors THE DOW CHEMICAL COMPANY (US) 1992-01-28 US disclosed
EP-0306547-A1 2-Hydrocarbyl-3,6-dichloropyridines and their preparation DOWELANCO (US) 1989-03-15 EP disclosed
EP-0306547-A1 2-Hydrocarbyl-3,6-dichloropyridines and their preparation DOWELANCO (US) 1989-03-15 EP disclosed
EP-0206078-A2 Herbicidal agent BAYER AG (DE) 1986-12-30 EP disclosed
US-4594422-A Hydroxylation of a 6-halo picolinic acid with a aqueous mineral acid solution; then halogenating THE DOW CHEMICAL COMPANY (US) 1986-06-10 US disclosed
EP-0046503-A1 Herbicidal agents on the the basis of cyclohexane-1,3-dione derivatives and 3,6-dichloro-2-picolinic-acid derivatives BASF Aktiengesellschaft (DE) 1982-03-03 EP disclosed