Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.60 |
| ▸ | CTSB | P07858 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6376636 | 1.00 | AR (0.60) | ARCTSBGAAALDH1A1LMNA | |
| SCHEMBL5088818 | 1.00 | AR (0.60) | ARCTSBGAAALDH1A1LMNA | |
| SCHEMBL4040367 | 1.00 | AR (0.60) | ARCTSBGAAALDH1A1LMNA | |
| SCHEMBL5099241 | 0.86 | AR (0.61) | ARCTSBGAALMNA | |
| SCHEMBL14033323 | 0.86 | AR (0.61) | ARCTSBGAALMNA | |
| SCHEMBL6375514 | 0.80 | AR (0.65) | ARCTSBGAAALDH1A1 | |
| SCHEMBL5099264 | 0.80 | AR (0.65) | ARCTSBGAAALDH1A1 | |
| SCHEMBL4039836 | 0.80 | AR (0.65) | ARCTSBGAAALDH1A1 | |
| SCHEMBL5092450 | 0.80 | AR (0.65) | ARCTSBGAAALDH1A1 | |
| SCHEMBL4037420 | 0.80 | AR (0.65) | ARCTSBGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1463728-B1 | FUSED CYCLIC MODULATORS OF NUCLEAR HORMONE RECEPTOR FUNCTION | BRISTOL MYERS SQUIBB CO (US) | 2009-01-14 | — | — | EP | disclosed |