Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4036450 | 0.95 | LCK (0.74) | LCKSRC | |
| SCHEMBL4036276 | 0.94 | LCK (0.72) | LCKSRC | |
| SCHEMBL4037788 | 0.91 | LCK (1.00) | LCKSRC | |
| SCHEMBL4036209 | 0.91 | LCK (1.00) | LCKSRC | |
| SCHEMBL4036207 | 0.91 | LCK (1.00) | LCKSRC | |
| SCHEMBL4038843 | 0.90 | LCK (0.76) | LCKSRC | |
| SCHEMBL4038248 | 0.90 | LCK (0.67) | LCKSRC | |
| SCHEMBL4038701 | 0.89 | LCK (0.74) | LCKSRC | |
| SCHEMBL4036075 | 0.87 | LCK (0.76) | LCKSRC | |
| SCHEMBL4038483 | 0.86 | LCK (0.75) | LCKSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620437-B1 | 5,7-DIAMINOPYRAZOLO¬4,3-D PYRIMIDINES USEFUL IN THE TRAETMENT OF HYPERTENSION | PFIZER LTD (GB) | 2009-06-17 | — | — | EP | claimed |
| EP-1066286-B1 | HETEROCYCLO-SUBSTITUTED IMIDAZOPYRAZINE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2009-04-29 | — | — | EP | claimed |
| EP-1549655-B1 | SUBSTITUTED BICYCLIC THIOPHENE DERIVATIVES, COMPOSTIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO INC (US) | 2009-01-21 | — | — | EP | claimed |
| EP-1066286-B1 | HETEROCYCLO-SUBSTITUTED IMIDAZOPYRAZINE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2009-04-29 | — | — | EP | disclosed |