Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.81 |
| ▸ | SRC | P12931 | 1/20 | 0.53 |
| ▸ | CETP | P11597 | 3/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.45 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27908642 | 0.90 | TSHR (1.00) | TSHRSRCCETPAKR1C3PDPK1 | |
| SCHEMBL51316 | 0.90 | TSHR (1.00) | TSHRSRCCETPAKR1C3PDPK1 | |
| SCHEMBL28032525 | 0.88 | TSHR (0.96) | TSHRSRCCETPAKR1C3PDPK1 | |
| Ammonia Solution, Strong SCHEMBL7268743 | 0.88 | TSHR (0.96) | TSHRSRCCETPAKR1C3PDPK1 | |
| SCHEMBL28264490 | 0.88 | TSHR (0.96) | TSHRSRCCETPAKR1C3PDPK1 | |
| SCHEMBL4219700 | 0.88 | TSHR (0.96) | TSHRSRCCETPAKR1C3PDPK1 | |
| Hydrochloric Acid SCHEMBL10722992 | 0.88 | TSHR (0.96) | TSHRSRCCETPAKR1C3PDPK1 | |
| SCHEMBL9446520 | 0.88 | TSHR (0.96) | TSHRSRCCETPAKR1C3PDPK1 | |
| SCHEMBL11756554 | 0.88 | TSHR (0.96) | TSHRSRCCETPAKR1C3PDPK1 | |
| Phosphoric Acid SCHEMBL27741297 | 0.88 | TSHR (0.96) | TSHRSRCCETPAKR1C3PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2931716-B1 | PYRIDONE DERIVATIVES AND USES THEREOF IN THE TREATMENT OF TUBERCULOSIS | NOVARTIS AG (CH) | 2016-11-02 | — | — | EP | disclosed |
| WO-2014093606-A1 | PYRIDONE DERIVATIVES AND USES THEREOF IN THE TREATMENT OF TUBERCULOSIS | NOVARTIS AG (CH) | 2014-06-19 | — | — | WO | disclosed |
| EP-2079699-A1 | QUINOLINE DERIVATIVES | Envivo Pharmaceuticals, Inc. (US) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008014602-A1 | QUINOLINE DERIVATIVES | ENVIVO PHARMACEUTICALS, INC. (US) | 2008-02-07 | — | — | WO | disclosed |