Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 15/20 | 0.47 |
| ▸ | ESR1 | P03372 | 3/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1366972 | 0.92 | MCHR1 (0.54) | MCHR1ESR1ESR2 | |
| SCHEMBL1364829 | 0.87 | MCHR1 (0.55) | MCHR1 | |
| SCHEMBL15310146 | 0.87 | MCHR1 (0.52) | MCHR1 | |
| SCHEMBL4538551 | 0.86 | MCHR1 (0.49) | MCHR1ESR1ESR2 | |
| SCHEMBL1368089 | 0.85 | MCHR1 (0.57) | MCHR1 | |
| SCHEMBL4056391 | 0.85 | MCHR1 (0.50) | MCHR1 | |
| SCHEMBL1365157 | 0.83 | MCHR1 (0.57) | MCHR1 | |
| SCHEMBL4047945 | 0.83 | MCHR1 (0.58) | MCHR1 | |
| SCHEMBL4047923 | 0.82 | MCHR1 (0.48) | MCHR1 | |
| SCHEMBL4046615 | 0.81 | MCHR1 (0.58) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103478-A1 | PYRIDONE AND PYRIDAZINONE DERIVATIVES AS MCH ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-08-27 | — | — | WO | disclosed |
| EP-1819676-A4 | 5-PHENYL-5,6,7,8-HYDROQUINOLINE TACHYKININ RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2009-04-15 | — | — | EP | disclosed |
| EP-1819676-A2 | 5-PHENYL-5,6,7,8-HYDROQUINOLINE TACHYKININ RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006060344-A2 | 5-PHENYL-5,6,7,8-HYDROQUINOLINE TACHYKININ RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2006-06-08 | — | — | WO | disclosed |