SCHEMBL404186

SCHEMBL404186

F[C](C(F)(F)F)C(F)(F)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2815953 0.84
SCHEMBL2816906 0.77
SCHEMBL2813365 0.77
SCHEMBL2811306 0.77
SCHEMBL2813386 0.77
SCHEMBL99135 0.74
SCHEMBL27191400 0.70
SCHEMBL28244892 0.70
SCHEMBL154019 0.70
SCHEMBL1272332 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2981519-B1 PROCESS FOR THE PREPARATION OF AMIDES FROM HINDERED ANILINES CONTAINING A PERHALOALKYL GROUP SYNGENTA PARTICIPATIONS AG (CH) 2018-08-01 EP claimed
US-9598369-B2 Process for the preparation of amides from hindered anilines containing a perhaloalkyl group SYNGENTA PARTICIPATIONS AG (CH) 2017-03-21 US claimed
US-20160168097-A1 PROCESS FOR THE PREPARATION OF AMIDES FROM HINDERED ANILINES CONTAINING A PERHALOALKYL GROUP SYNGENTA PARTICIPATIONS AG (CH) 2016-06-16 US claimed
EP-2981519-A1 PROCESS FOR THE PREPARATION OF AMIDES FROM HINDERED ANILINES CONTAINING A PERHALOALKYL GROUP Syngenta Participations AG (CH) 2016-02-10 EP claimed
WO-2014161850-A1 PROCESS FOR THE PREPARATION OF AMIDES FROM HINDERED ANILINES CONTAINING A PERHALOALKYL GROUP SYNGENTA PARTICIPATIONS AG (CH) 2014-10-09 WO claimed
EP-2981519-B1 PROCESS FOR THE PREPARATION OF AMIDES FROM HINDERED ANILINES CONTAINING A PERHALOALKYL GROUP SYNGENTA PARTICIPATIONS AG (CH) 2018-08-01 EP disclosed
CN-104736148-B Parazoon expeling composition and the expelling method of parazoon 三井化学AGRO株式会社 2018-01-12 CN disclosed
US-9598369-B2 Process for the preparation of amides from hindered anilines containing a perhaloalkyl group SYNGENTA PARTICIPATIONS AG (CH) 2017-03-21 US disclosed
US-9381174-B2 Composition and method for exterminating animal parasite MITSUI CHEMICALS AGRO, INC. (JP) 2016-07-05 US disclosed
US-20160168097-A1 PROCESS FOR THE PREPARATION OF AMIDES FROM HINDERED ANILINES CONTAINING A PERHALOALKYL GROUP SYNGENTA PARTICIPATIONS AG (CH) 2016-06-16 US disclosed
EP-2981519-A1 PROCESS FOR THE PREPARATION OF AMIDES FROM HINDERED ANILINES CONTAINING A PERHALOALKYL GROUP Syngenta Participations AG (CH) 2016-02-10 EP disclosed
US-20150297541-A1 COMPOSITION AND METHOD FOR EXTERMINATING ANIMAL PARASITE MITSUI CHEMICALS AGRO, INC. (JP) 2015-10-22 US disclosed
US-20090216030-A1 METHOD OF MANUFACTURING PERFLUORINATED POLYFUNCTIONAL VINYL ETHER COMPOUND FUJIFILM CORPORATION (JP) 2009-08-27 US disclosed
CN-100522903-C Polyhalide alkaryl compound BAYER AG (DE) 2009-08-05 CN disclosed
EP-1418169-B1 Process for the preparation of polyhalogenoalkylaryl compounds SALTIGO GMBH (DE) 2009-02-25 EP disclosed
EP-1933895-A2 STENT WITH POCKETS FOR CONTAINING A THERAPEUTIC AGENT Boston Scientific Limited (BB) 2008-06-25 EP disclosed
WO-2007030534-A2 STENT WITH POCKETS CONTAINING A THERAPEUTIC AGENT BOSTON SCIENTIFIC LIMITED (BB) 2007-03-15 WO disclosed
CN-1498881-A Polyhalide alkaryl compound 2004-05-26 CN disclosed
US-20040092762-A1 Polyhaloalkylaryls LANXESS DEUTSCHLAND GMBH (DE) 2004-05-13 US disclosed
EP-1418169-A2 Polyhalogenoalkylaryl compounds Bayer Chemicals AG (DE) 2004-05-12 EP disclosed