SCHEMBL4041909

SCHEMBL4041909

COC([C]=O)C(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8789015 0.77
SCHEMBL4042478 0.73
SCHEMBL15332553 0.68
SCHEMBL10414189 0.67 TSHR (0.48)
SCHEMBL1951265 0.67
SCHEMBL57048 0.67
SCHEMBL1951911 0.67
SCHEMBL269360 0.65
SCHEMBL1483243 0.63
SCHEMBL570696 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3762037-A1 RELEASABLE ANTIBODY CONJUGATES QuiaPEG Pharmaceuticals AB (SE) 2021-01-13 EP claimed
WO-2019171358-A1 RELEASABLE ANTIBODY CONJUGATES QUIAPEG PHARMACEUTICALS AB (SE) 2019-09-12 WO claimed
WO-2018163131-A1 RELEASABLE CONJUGATES QUIAPEG PHARMACEUTICALS AB (SE) 2018-09-13 WO claimed
EP-1546150-B1 PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES AMURA THERAPEUTICS LTD (GB) 2009-03-04 EP claimed
US-20060100431-A1 Biologically active compounds AMURA THERAPEUTICS LIMITED (GB) 2006-05-11 US claimed
EP-1546150-A1 BIOLOGICALLY ACTIVE COMPOUNDS Amura Therapeutics Limited (GB) 2005-06-29 EP claimed
WO-2004007501-A1 BIOLOGICALLY ACTIVE COMPOUNDS AMURA THERAPEUTICS LIMITED (GB) 2004-01-22 WO claimed
US-20240181017-A1 RELEASABLE GLP-1 CONJUGATES QUIAPEG PHARMACEUTICALS AB (SE) 2024-06-06 US disclosed
US-11957735-B2 Releasable GLP-1 conjugates QUIAPEG PHARMACEUTICALS AB (SE) 2024-04-16 US disclosed
US-20240075150-A1 CONJUGATES COMPRISING REVERSIBLE LINKERS AND USES THEREOF ASCENDIS PHARMA A/S (DK) 2024-03-07 US disclosed
EP-3762037-B1 RELEASABLE ANTIBODY CONJUGATES QUIAPEG PHARMACEUTICALS AB (SE) 2023-12-27 EP disclosed
US-20230381323-A1 RELEASABLE CONJUGATES FISH & RICHARDSON PC 2023-11-30 US disclosed
US-11786599-B2 Releasable conjugates QUIAPEG PHARMACEUTICALS AB (SE) 2023-10-17 US disclosed
US-20130281455-A1 Phenylpyri(mi)dinylazoles BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-10-24 US disclosed
EP-1546150-B1 PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES AMURA THERAPEUTICS LTD (GB) 2009-03-04 EP disclosed
EP-1463728-B1 FUSED CYCLIC MODULATORS OF NUCLEAR HORMONE RECEPTOR FUNCTION BRISTOL MYERS SQUIBB CO (US) 2009-01-14 EP disclosed
WO-2007006714-A1 CYSTEINE PROTEASE INHIBITORS MEDIVIR AB (SE) 2007-01-18 WO disclosed
US-20060100431-A1 Biologically active compounds AMURA THERAPEUTICS LIMITED (GB) 2006-05-11 US disclosed
EP-1546150-A1 BIOLOGICALLY ACTIVE COMPOUNDS Amura Therapeutics Limited (GB) 2005-06-29 EP disclosed
WO-2004007501-A1 BIOLOGICALLY ACTIVE COMPOUNDS AMURA THERAPEUTICS LIMITED (GB) 2004-01-22 WO disclosed