SCHEMBL40422

SCHEMBL40422

NC1CCCc2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 4/20 0.58
HTR2A P28223 2/20 0.45
RET P07949 1/20 0.45
TSHR P16473 1/20 0.44
ADRA2A P08913 2/20 0.44
ADRA1A P35348 2/20 0.44
LMNA P02545 1/20 0.44
ADRA1D P25100 1/20 0.44
ADRA1B P35368 1/20 0.44
HTR1A P08908 1/20 0.44
OPRM1 P35372 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29415502 1.00 IDO1 (0.58) IDO1HTR2ARETTSHRADRA2A
SCHEMBL30837489 1.00 IDO1 (0.58) IDO1HTR2ARETTSHRADRA2A
SCHEMBL14543304 1.00 IDO1 (0.58) IDO1HTR2ARETTSHRADRA2A
SCHEMBL10774751 1.00 IDO1 (0.58) IDO1HTR2ARETTSHRADRA2A
SCHEMBL44600 1.00 IDO1 (0.58) IDO1HTR2ARETTSHRADRA2A
SCHEMBL469047 1.00 IDO1 (0.58) IDO1HTR2ARETTSHRADRA2A
Bromide SCHEMBL3727459 0.98 IDO1 (0.56) IDO1HTR2ARETADRA2AADRA1A
Methane SCHEMBL9503230 0.98 IDO1 (0.56) IDO1HTR2ARETADRA2AADRA1A
Hydrochloric Acid SCHEMBL7424398 0.98 IDO1 (0.59) IDO1HTR2ARET
Hydrochloric Acid SCHEMBL29757860 0.98 IDO1 (0.59) IDO1HTR2ARET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2700 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12491141-B2 Dental root canal filling composition DENTSPLY SIRONA INC. (US) 2025-12-09 US claimed
CN-120192449-A Maleimide high heat-resistant impact modifier and preparation method thereof 浙江烯苯醇新材料科技有限公司 2025-06-24 CN claimed
US-20250145472-A1 METHOD FOR GENERATING CARBON DIOXIDE KOBE GAKUIN EDUCATIONAL FOUNDATION (JP) 2025-05-08 US claimed
CN-119923178-A Thiopyran molecular modified solar cell and preparation method thereof 昆明理工大学 2025-05-02 CN claimed
US-20250075147-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEW FLAVOR AND FRAGRANCE INGREDIENTS OSMO LABS, PBC 2025-03-06 US claimed
EP-4480568-A1 METHOD FOR GENERATING CARBON DIOXIDE Kobe Gakuin Educational Foundation (JP) 2024-12-25 EP claimed
CN-118812866-B Nano-enzyme, preparation method thereof and application thereof in estrogen detection 云南省第一人民医院 2024-12-06 CN claimed
CN-118978493-A Nonplanar nile blue photosensitizer, synthesis method and application thereof 大连理工大学宁波研究院 2024-11-19 CN claimed
CN-118812866-A Nano-enzyme, preparation method thereof and application thereof in estrogen detection 云南省第一人民医院 2024-10-22 CN claimed
CN-118591538-A Pyrazinamide derivatives 诺华股份有限公司 2024-09-03 CN claimed
EP-0575507-A1 PROCESS FOR RECYCLING AMINE ISOMER. PFIZER (US) 1993-12-29 EP claimed
US-5206418-A Thromboxan A2 antagonist TANABE SEIYAKU CO., LTD. (JP) 1993-04-27 US claimed
US-5192759-A Cognition activators, learning enhancement SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 1993-03-09 US claimed
WO-1992015552-A1 PROCESS FOR RECYCLING AMINE ISOMER PFIZER INC. (US) 1992-09-17 WO claimed
EP-0493346-A2 Derivatives of 1,2,3,4-tetrahydronaphtylamine endowed with nootropic activity and pharmaceutical compositions containing same Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) 1992-07-01 EP claimed
CN-1052112-A Naphthyl  oxazolidinone derivative TANABE SEIYAKU CO (JP) 1991-06-12 CN claimed
EP-0430459-A1 Tetrahydronaphthalene derivatives and preparation thereof TANABE SEIYAKU CO., LTD. (JP) 1991-06-05 EP claimed
EP-0166321-B1 HYDROPHOBIC POLYAMIDES BAYER AG (DE) 1990-08-08 EP claimed
CN-87107539-A The alkaline 2-amino-1,2,3,4-tetralin that replaces 1988-07-13 CN claimed
US-4616053-A Hydrophobic polyamides BAYER AKTIENGESELLSCHAFT (DE) 1986-10-07 US claimed