Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 20/20 | 0.71 |
| ▸ | HTR2C | P28335 | 12/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4040378 | 0.92 | HTR2A (0.81) | HTR2AHTR2CKCNH2 | |
| SCHEMBL3944615 | 0.92 | HTR2A (0.79) | HTR2AHTR2CKCNH2 | |
| SCHEMBL4045180 | 0.91 | HTR2A (0.84) | HTR2AHTR2CKCNH2 | |
| SCHEMBL3947291 | 0.90 | HTR2A (0.76) | HTR2AHTR2CKCNH2 | |
| SCHEMBL3948218 | 0.90 | HTR2A (0.74) | HTR2AHTR2CKCNH2 | |
| SCHEMBL3947258 | 0.89 | HTR2A (0.77) | HTR2AHTR2CKCNH2 | |
| SCHEMBL1165805 | 0.89 | HTR2A (0.72) | HTR2AHTR2CKCNH2 | |
| SCHEMBL4034556 | 0.88 | HTR2A (0.70) | HTR2AHTR2CKCNH2 | |
| Water SCHEMBL2016094 | 0.86 | HTR2A (0.82) | HTR2AHTR2CKCNH2 | |
| SCHEMBL1166313 | 0.86 | HTR2A (0.68) | HTR2AHTR2CKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2051978-A2 | ACETAMIDE DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | Arena Pharmaceuticals, Inc. (US) | 2009-04-29 | — | — | EP | disclosed |
| WO-2007136875-A2 | ACETAMIDE DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2007-11-29 | — | — | WO | disclosed |