Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13887312 | 0.88 | KCNH2 (0.47) | KCNH2 | |
| SCHEMBL3581606 | 0.88 | KCNH2 (0.47) | KCNH2 | |
| Hydrochloric Acid SCHEMBL3581512 | 0.87 | KCNH2 (0.46) | KCNH2 | |
| SCHEMBL5927783 | 0.77 | KCNH2 (0.56) | KCNH2 | |
| Hydrochloric Acid SCHEMBL4498000 | 0.76 | KCNH2 (0.55) | KCNH2 | |
| SCHEMBL13439991 | 0.76 | KCNH2 (0.47) | KCNH2 | |
| SCHEMBL5262915 | 0.74 | KCNH2 (0.38) | KCNH2 | |
| SCHEMBL13407438 | 0.74 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL14498890 | 0.74 | KCNH2 (0.60) | KCNH2 | |
| SCHEMBL5259010 | 0.74 | KCNH2 (0.38) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537123-B1 | AMINO-SUBSTITUTED CYCLOHEXANE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS | GLAXO GROUP LTD (GB) | 2009-04-29 | — | — | EP | claimed |