Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4039035 | 0.98 | LCK (0.58) | LCKSRC | |
| SCHEMBL4040554 | 0.94 | LCK (0.53) | LCKSRC | |
| SCHEMBL4039646 | 0.92 | LCK (0.54) | LCKSRC | |
| SCHEMBL4038240 | 0.91 | LCK (0.61) | LCKSRC | |
| SCHEMBL4039834 | 0.86 | LCK (0.56) | LCKSRC | |
| SCHEMBL4037499 | 0.86 | LCK (0.56) | LCKSRC | |
| SCHEMBL4038056 | 0.86 | LCK (0.56) | LCKSRC | |
| SCHEMBL4045072 | 0.85 | LCK (0.54) | LCKSRC | |
| SCHEMBL4037062 | 0.84 | LCK (0.57) | LCKSRC | |
| SCHEMBL4039987 | 0.80 | LCK (0.71) | LCKSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066286-B1 | HETEROCYCLO-SUBSTITUTED IMIDAZOPYRAZINE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2009-04-29 | — | — | EP | claimed |