Ethylene

Ethylene

SCHEMBL4043660

C=C.C=C.C=C.Cc1cc(CCC(=O)O)cc(C(C)(C)C)c1O.Cc1cc(CCC(=O)O)cc(C(C)(C)C)c1O

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.52
KMT2A Q03164 4/20 0.49
MEN1 O00255 3/20 0.47
CYP1A2 P05177 2/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
RXRA P19793 1/20 0.42
RXRB P28702 1/20 0.42
RXRG P48443 1/20 0.42
NPSR1 Q6W5P4 2/20 0.42
ALDH1A1 P00352 2/20 0.42
LMNA P02545 1/20 0.42
AGTR1 P30556 1/20 0.42
HTT P42858 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
THRA P10827 1/20 0.41
THRB P10828 1/20 0.41
GLRA3 O75311 1/20 0.41
GLRB P48167 1/20 0.41
MAOA P21397 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL21753792 1.00 GAA (0.52) GAAKMT2AMEN1CYP1A2CYP2C9
Ethylene SCHEMBL27695680 1.00 GAA (0.52) GAAKMT2AMEN1CYP1A2CYP2C9
Hydrogen Peroxide SCHEMBL28104512 0.97 GAA (0.55) GAAKMT2AMEN1CYP1A2CYP2C9
SCHEMBL39866 0.97 GAA (0.55) GAAKMT2AMEN1CYP1A2CYP2C9
SCHEMBL29387462 0.97 GAA (0.55) GAAKMT2AMEN1CYP1A2CYP2C9
Ammonia Solution, Strong SCHEMBL5491694 0.95 GAA (0.54) GAAKMT2AMEN1CYP1A2CYP2C9
Methane SCHEMBL28345434 0.95 GAA (0.54) GAAKMT2AMEN1CYP1A2CYP2C9
SCHEMBL28324794 0.95 GAA (0.57) GAAKMT2AMEN1CYP1A2CYP2C9
SCHEMBL5028593 0.94 GAA (0.52) GAAKMT2AMEN1CYP1A2CYP2C9
Ethylene Glycol SCHEMBL8407093 0.93 GAA (0.51) GAAKMT2AMEN1CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2035470-A1 THERMOPLASTIC RESIN COMPOSITIONS SUITABLE FOR USE IN TRANSPARENT LAMINATES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-03-18 EP disclosed
WO-2007149082-A1 THERMOPLASTIC RESIN COMPOSITIONS SUITABLE FOR USE IN TRANSPARENT LAMINATES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-12-27 WO disclosed
US-20070289693-A1 Thermoplastic resin compositions suitable for use in transparent laminates E. I. DU PONT DE NEMOURS AND COMPANY 2007-12-20 US disclosed