Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 7/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AHCY | P23526 | 3/20 | 0.36 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.36 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4039404 | 0.92 | GCGR (0.72) | GCGRTP53ALDH1A1MAPTNPSR1 | |
| SCHEMBL4038691 | 0.85 | GCGR (0.82) | GCGRTP53ALDH1A1MAPTNPSR1 | |
| SCHEMBL4043143 | 0.83 | GCGR (0.79) | GCGRTP53ALDH1A1MAPTNPSR1 | |
| SCHEMBL4039309 | 0.83 | GCGR (0.75) | GCGRTP53ALDH1A1MAPTLMNA | |
| SCHEMBL4035262 | 0.82 | GCGR (0.82) | GCGRTP53ALDH1A1MAPTNPC1 | |
| SCHEMBL4040281 | 0.82 | GCGR (0.82) | GCGRTP53ALDH1A1MAPTNPSR1 | |
| SCHEMBL4037039 | 0.82 | GCGR (0.78) | GCGRTP53ALDH1A1MAPTNPSR1 | |
| SCHEMBL4042010 | 0.81 | GCGR (0.80) | GCGRTP53ALDH1A1MAPTNPSR1 | |
| SCHEMBL4036939 | 0.81 | GCGR (0.78) | GCGRTP53ALDH1A1MAPTNPSR1 | |
| SCHEMBL4045348 | 0.81 | GCGR (0.67) | GCGRTP53ALDH1A1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549655-B1 | SUBSTITUTED BICYCLIC THIOPHENE DERIVATIVES, COMPOSTIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO INC (US) | 2009-01-21 | — | — | EP | claimed |