Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.74 |
| ▸ | MCHR1 | Q99705 | 11/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1364816 | 0.86 | MCHR1 (0.82) | MAPK14MCHR1KCNH2 | |
| SCHEMBL2177074 | 0.86 | MAPK14 (1.00) | MAPK14MCHR1 | |
| SCHEMBL1364736 | 0.84 | MCHR1 (0.73) | MAPK14MCHR1KCNH2 | |
| SCHEMBL1365313 | 0.84 | MCHR1 (0.73) | MAPK14MCHR1KCNH2 | |
| SCHEMBL4480114 | 0.84 | MAPK14 (0.84) | MAPK14MCHR1KCNH2 | |
| SCHEMBL2176073 | 0.83 | MAPK14 (0.86) | MAPK14MCHR1 | |
| SCHEMBL2174876 | 0.82 | MAPK14 (0.84) | MAPK14MCHR1 | |
| SCHEMBL4468505 | 0.82 | MAPK14 (0.84) | MAPK14MCHR1 | |
| SCHEMBL2175898 | 0.82 | MAPK14 (0.84) | MAPK14MCHR1 | |
| SCHEMBL4468571 | 0.82 | MAPK14 (0.84) | MAPK14MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103478-A1 | PYRIDONE AND PYRIDAZINONE DERIVATIVES AS MCH ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-08-27 | — | — | WO | disclosed |
| WO-2009103478-A1 | PYRIDONE AND PYRIDAZINONE DERIVATIVES AS MCH ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-08-27 | — | — | WO | disclosed |