SCHEMBL4046006

SCHEMBL4046006

O=C(Cn1ccc(OCc2ccc(Cl)cn2)cc1=O)c1ccc(CO)cc1

nearest known ligand 0.79

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 20/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4053384 0.91 MCHR1 (0.78) MCHR1
SCHEMBL15249808 0.89 MCHR1 (1.00) MCHR1
SCHEMBL4045084 0.88 MCHR1 (0.79) MCHR1
SCHEMBL15238511 0.88 MCHR1 (0.82) MCHR1
SCHEMBL2879663 0.87 MCHR1 (0.60) MCHR1
SCHEMBL1367992 0.84 MCHR1 (0.79) MCHR1
SCHEMBL15238697 0.81 MCHR1 (0.84) MCHR1
SCHEMBL4048098 0.80 MCHR1 (0.79) MCHR1
SCHEMBL15238666 0.80 MCHR1 (1.00) MCHR1
SCHEMBL1365451 0.80 MCHR1 (0.77) MCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009103478-A1 PYRIDONE AND PYRIDAZINONE DERIVATIVES AS MCH ANTAGONISTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2009-08-27 WO disclosed