SCHEMBL4046148

SCHEMBL4046148

C#CC[Si](C)(C)CCC(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10745558 0.77
SCHEMBL4313662 0.74
SCHEMBL21924510 0.71
SCHEMBL4320494 0.70
SCHEMBL31139494 0.69
SCHEMBL2806612 0.69
SCHEMBL2761275 0.67 SMN1; SMN2 (0.30)
SCHEMBL3889963 0.66
SCHEMBL20980047 0.65 NR1H2 (0.34)
SCHEMBL4317358 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070255014-A1 Gas-permeable materials and medical devices SOLTA MEDICAL, INC. 2007-11-01 US claimed
EP-1778388-B1 MEMBRANE GAZ SEPERATION TNO (NL) 2012-06-06 EP disclosed
US-7591878-B2 Separating CO2 from CO2-rich liquid comprising step in which under elevated pressure liquid is contacted with membrane based on polyacetylene substituted with trimethylsilyl groups, while pressure difference across membrane is at least 1 bar and while at least part of CO2 is transported through membrane NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2009-09-22 US disclosed
US-20070214957-A1 Separating CO2 from CO2-rich liquid comprising step in which under elevated pressure liquid is contacted with membrane based on polyacetylene substituted with trimethylsilyl groups, while pressure difference across membrane is at least 1 bar and while at least part of CO2 is transported through membrane NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2007-09-20 US disclosed
EP-1778388-A1 MEMBRANE GAZ SEPERATION Nederlandse Organisatie voor Toegepast-Natuuurwetenschappelijk Onderzoek TNO (NL) 2007-05-02 EP disclosed
WO-2006004400-A1 MEMBRANE GAZ SEPERATION NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2006-01-12 WO disclosed
EP-0237581-B1 POLY(DI-SUBSTITUTED ACETYLENE)/POLYORGANOSILOXANE GRAFT COPOLYMER AND GAS SEPARATION MEMBRANE SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-12-27 EP disclosed
US-4755561-A Poly(disubstituted acetylene)/polyorganosiloxane graft copolymer and membrane for gas separation SAGAMI CHEMICAL RESEARCH CENTER (JP) 1988-07-05 US disclosed
US-4746334-A OXYGEN SEPARATORS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1988-05-24 US disclosed
EP-0237581-A1 POLY(DI-SUBSTITUTED ACETYLENE)/POLYORGANOSILOXANE GRAFT COPOLYMER AND GAS SEPARATION MEMBRANE SAGAMI CHEMICAL RESEARCH CENTER (JP) 1987-09-23 EP disclosed