Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 18/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4053710 | 0.87 | MCHR1 (0.49) | MCHR1 | |
| SCHEMBL1364697 | 0.86 | MCHR1 (0.51) | MCHR1NR1H2 | |
| SCHEMBL4046203 | 0.85 | NR1H2 (0.46) | MCHR1NR1H2ESR2 | |
| SCHEMBL4049028 | 0.79 | MCHR1 (0.52) | MCHR1 | |
| SCHEMBL4050118 | 0.79 | MCHR1 (0.43) | MCHR1 | |
| SCHEMBL4215749 | 0.79 | MCHR1 (0.49) | MCHR1NR1H2ESR2 | |
| SCHEMBL1367079 | 0.78 | MCHR1 (0.48) | MCHR1NR1H2ESR2 | |
| SCHEMBL4054145 | 0.77 | MCHR1 (0.51) | MCHR1NR1H2ESR2 | |
| SCHEMBL1365157 | 0.77 | MCHR1 (0.57) | MCHR1 | |
| SCHEMBL1367258 | 0.76 | MCHR1 (0.43) | MCHR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103478-A1 | PYRIDONE AND PYRIDAZINONE DERIVATIVES AS MCH ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-08-27 | — | — | WO | disclosed |