Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 18/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL158142 | 1.00 | CYP4F2 (0.45) | CYP4F2CYP4A11MCHR1 | |
| SCHEMBL1366940 | 0.88 | CYP4F2 (0.46) | CYP4F2CYP4A11MCHR1 | |
| SCHEMBL1364562 | 0.87 | MCHR1 (0.44) | CYP4F2CYP4A11MCHR1 | |
| SCHEMBL1365511 | 0.87 | MCHR1 (0.44) | CYP4F2CYP4A11MCHR1 | |
| SCHEMBL15238669 | 0.86 | MCHR1 (0.45) | CYP4F2CYP4A11MCHR1 | |
| SCHEMBL4047527 | 0.84 | MCHR1 (0.49) | MCHR1 | |
| SCHEMBL1366609 | 0.84 | CYP4F2 (0.46) | CYP4F2CYP4A11MCHR1 | |
| SCHEMBL1366880 | 0.81 | CYP4F2 (0.51) | CYP4F2CYP4A11MCHR1 | |
| SCHEMBL15111078 | 0.80 | MCHR1 (0.45) | CYP4F2CYP4A11MCHR1 | |
| SCHEMBL155870 | 0.78 | CYP4F2 (0.44) | CYP4F2CYP4A11MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103478-A1 | PYRIDONE AND PYRIDAZINONE DERIVATIVES AS MCH ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-08-27 | — | — | WO | disclosed |