Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | UTRN | P46939 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | AHR | P35869 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.52 |
| ▸ | PTPN5 | P54829 | 3/20 | 0.52 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.52 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2243999 | 0.90 | UTRN (0.70) | LMNAPOLBMAPTUTRNCYP1A2 | |
| SCHEMBL3949747 | 0.87 | UTRN (0.57) | LMNAPOLBTP53MAPTUTRN | |
| SCHEMBL27652467 | 0.86 | MAPT (0.58) | LMNAPOLBTP53MAPTPTPN2 | |
| SCHEMBL26686674 | 0.85 | TP53 (0.56) | LMNATP53MAPTUTRNCYP1A2 | |
| SCHEMBL2244328 | 0.85 | UTRN (0.60) | LMNAPOLBMAPTUTRNCYP1A2 | |
| SCHEMBL19664251 | 0.85 | UTRN (0.54) | LMNAPOLBTP53MAPTUTRN | |
| SCHEMBL2245432 | 0.81 | UTRN (0.59) | LMNAPOLBMAPTUTRNCYP1A2 | |
| SCHEMBL10590678 | 0.78 | SMN1; SMN2 (0.61) | LMNAPOLBTP53MAPTGPR119 | |
| SCHEMBL2244375 | 0.77 | UTRN (0.71) | LMNAPOLBTP53MAPTUTRN | |
| SCHEMBL2247922 | 0.77 | UTRN (0.70) | POLBMAPTUTRNCYP1A2AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009021750-A2 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT CORPORATION PLC (GB) | 2009-02-19 | — | — | WO | disclosed |