Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 18/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13748370 | 0.91 | MCHR1 (0.59) | MCHR1NPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL4046477 | 0.91 | MCHR1 (0.59) | MCHR1NPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL4044442 | 0.90 | MCHR1 (0.60) | MCHR1 | |
| SCHEMBL4045465 | 0.90 | MCHR1 (0.60) | MCHR1 | |
| SCHEMBL4047703 | 0.81 | MCHR1 (0.59) | MCHR1 | |
| SCHEMBL15310200 | 0.78 | MCHR1 (0.62) | MCHR1 | |
| SCHEMBL1365451 | 0.76 | MCHR1 (0.77) | MCHR1 | |
| SCHEMBL2876830 | 0.76 | MCHR1 (0.67) | MCHR1 | |
| SCHEMBL1366725 | 0.75 | MCHR1 (0.75) | MCHR1 | |
| SCHEMBL15249806 | 0.75 | MCHR1 (1.00) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103478-A1 | PYRIDONE AND PYRIDAZINONE DERIVATIVES AS MCH ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-08-27 | — | — | WO | disclosed |
| WO-2009103478-A1 | PYRIDONE AND PYRIDAZINONE DERIVATIVES AS MCH ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-08-27 | — | — | WO | disclosed |