Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 16/20 | 1.00 |
| ▸ | ABCG2 | Q9UNQ0 | 15/20 | 1.00 |
| ▸ | TNF | P01375 | 1/20 | 0.62 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.62 |
| ▸ | DRD2 | P14416 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7169032 | 0.92 | ABCB1 (0.85) | ABCB1ABCG2TNFNOD1DRD2 | |
| SCHEMBL4047473 | 0.89 | ABCB1 (0.80) | ABCB1ABCG2TNFNOD1DRD2 | |
| SCHEMBL7168885 | 0.89 | ABCB1 (0.80) | ABCB1ABCG2 | |
| SCHEMBL3885917 | 0.86 | ABCB1 (1.00) | ABCB1ABCG2 | |
| SCHEMBL4046056 | 0.86 | ABCB1 (0.75) | ABCB1ABCG2 | |
| SCHEMBL7168551 | 0.86 | ABCG2 (0.75) | ABCB1ABCG2 | |
| SCHEMBL4041119 | 0.85 | ABCB1 (0.83) | ABCB1ABCG2 | |
| SCHEMBL4048152 | 0.84 | ABCB1 (0.72) | ABCB1ABCG2 | |
| SCHEMBL7167675 | 0.81 | ABCB1 (0.90) | ABCB1ABCG2 | |
| SCHEMBL7169029 | 0.81 | ABCB1 (0.67) | ABCB1ABCG2TNFNOD1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934276-B1 | ANTHRANILIC ACID DERIVATIVES AS MULTI DRUG RESISTANCE MODULATORS | XENOVA LTD (GB) | 2003-12-17 | — | — | EP | claimed |
| US-6218393-B1 | IN THERAPY OF MULTIDRUG RESISTANT CANCERS, FOR EXAMPLE TO POTENTIATE CYTOTOXICITY OF CANCER DRUG | XENOVA LIMITED (GB) | 2001-04-17 | — | — | US | claimed |
| EP-1506188-B1 | PROCESS FOR THE PREPARATION OF A HYDRATE OF AN ANTHRANILIC ACID DERIVATIVE | XENOVA LTD (GB) | 2009-02-25 | — | — | EP | disclosed |