Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 20/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 20/20 | 0.54 |
| ▸ | ADORA2B | P29275 | 20/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4045447 | 0.88 | ADORA2A (0.64) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL4048420 | 0.81 | ADORA2A (0.71) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL2990217 | 0.75 | ADORA2A (0.72) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL2982478 | 0.74 | ADORA2A (0.75) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL4047290 | 0.73 | ADORA2A (0.66) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL2845343 | 0.73 | ADORA2A (0.75) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL13707386 | 0.73 | ADORA2A (0.82) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL4044630 | 0.72 | ADORA2A (0.67) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL2990702 | 0.72 | ADORA2A (1.00) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL4046632 | 0.71 | ADORA2A (0.75) | ADORA3ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392312-B1 | TRIAZOLO 4,5-d PYRIMIDINE DERIVATIVES AND THEIR USE AS PURINERGIC RECEPTOR ANTAGONISTS | VERNALIS RES LTD (GB) | 2009-03-04 | — | — | EP | claimed |