Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4044654 | 0.97 | MCHR1 (0.61) | MCHR1 | |
| SCHEMBL4045545 | 0.90 | MCHR1 (0.61) | MCHR1 | |
| SCHEMBL13748832 | 0.90 | MCHR1 (0.51) | MCHR1 | |
| SCHEMBL4043510 | 0.88 | MCHR1 (0.47) | MCHR1 | |
| SCHEMBL1367344 | 0.86 | MCHR1 (0.61) | MCHR1 | |
| SCHEMBL4049081 | 0.86 | MCHR1 (0.61) | MCHR1 | |
| SCHEMBL1365688 | 0.84 | MCHR1 (0.50) | MCHR1 | |
| SCHEMBL4044436 | 0.84 | MCHR1 (0.63) | MCHR1 | |
| SCHEMBL4050579 | 0.83 | MCHR1 (0.62) | MCHR1 | |
| SCHEMBL1366019 | 0.82 | MCHR1 (0.44) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069327-B1 | NEW PYRIDONE DERIVATIVES WITH MCH ANTAGONISTIC ACTIVITY AND MEDICAMENTS COMPRISING THESE COMPOUNDS | BOEHRINGER INGELHEIM INT (DE) | 2013-10-16 | — | — | EP | claimed |
| WO-2009103478-A1 | PYRIDONE AND PYRIDAZINONE DERIVATIVES AS MCH ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-08-27 | — | — | WO | disclosed |