Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.61 |
| ▸ | CNR2 | P34972 | 3/20 | 0.48 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 6/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4050611 | 0.91 | CNR1 (0.63) | CNR1CNR2HTR4ACHEHTR3A | |
| SCHEMBL4054508 | 0.91 | CNR1 (0.63) | CNR1CNR2HTR4ACHEHTR3A | |
| SCHEMBL13691030 | 0.91 | CNR1 (0.63) | CNR1CNR2HTR4ACHEHTR3A | |
| SCHEMBL4057048 | 0.90 | CNR1 (0.61) | CNR1CNR2HTR4ACHEHTR3A | |
| SCHEMBL4048912 | 0.90 | CNR1 (0.61) | CNR1CNR2HTR4ACHEHTR3A | |
| SCHEMBL13690936 | 0.90 | CNR1 (0.61) | CNR1CNR2HTR4ACHEHTR3A | |
| SCHEMBL4049454 | 0.88 | CNR1 (0.63) | CNR1CNR2HTR4ACHEHTR3A | |
| SCHEMBL13690661 | 0.87 | CNR1 (0.59) | CNR1CNR2HTR4ACHEHTR3A | |
| SCHEMBL29019177 | 0.87 | CNR1 (0.67) | CNR1CNR2HTR4ACHEHTR3A | |
| SCHEMBL30353005 | 0.87 | CNR1 (0.67) | CNR1CNR2HTR4ACHEHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |