Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 12/20 | 0.56 |
| ▸ | CNR2 | P34972 | 9/20 | 0.56 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13690609 | 1.00 | CNR1 (0.56) | CNR1CNR2SCN9AEGFRSRC | |
| SCHEMBL13691161 | 0.89 | CNR1 (0.62) | CNR1CNR2HTR3AKDM4E | |
| SCHEMBL4048639 | 0.89 | CNR1 (0.58) | CNR1CNR2SCN9AHTR3AKDM4E | |
| SCHEMBL4051781 | 0.89 | CNR1 (0.43) | CNR1CNR2SCN9A | |
| SCHEMBL4049921 | 0.89 | CNR1 (0.43) | CNR1CNR2SCN9A | |
| SCHEMBL13690974 | 0.88 | CNR1 (0.58) | CNR1CNR2HTR3AKDM4EHDAC1 | |
| SCHEMBL4051603 | 0.88 | CNR1 (0.58) | CNR1CNR2HTR3AKDM4EHDAC1 | |
| SCHEMBL4057247 | 0.88 | CNR1 (0.59) | CNR1CNR2HTR3AKDM4EHDAC1 | |
| SCHEMBL13690654 | 0.87 | CNR1 (0.57) | CNR1CNR2SCN9AEGFRSRC | |
| SCHEMBL13690913 | 0.87 | CNR1 (0.58) | CNR1CNR2HTR3AKDM4EHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |