Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3258755 | 0.85 | CNR2 (0.42) | CNR2 | |
| SCHEMBL3257344 | 0.83 | CNR2 (0.42) | CNR2 | |
| SCHEMBL3247566 | 0.82 | CNR2 (0.62) | CNR2 | |
| SCHEMBL3247560 | 0.82 | CNR2 (0.62) | CNR2 | |
| SCHEMBL3252978 | 0.82 | CNR2 (0.62) | CNR2 | |
| SCHEMBL3254967 | 0.81 | CNR2 (0.52) | CNR2 | |
| SCHEMBL3253623 | 0.80 | CNR2 (0.62) | CNR2 | |
| SCHEMBL3250448 | 0.80 | CNR2 (0.62) | CNR2 | |
| SCHEMBL3250454 | 0.80 | CNR2 (0.62) | CNR2 | |
| SCHEMBL3256340 | 0.80 | CNR2 (0.52) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2076499-A2 | PYRAZINE-2-CARBOXAMIDE DERIVATIVES AS CB2 RECEPTOR MODULATORS | F.HOFFMANN-LA ROCHE AG (CH) | 2009-07-08 | — | — | EP | disclosed |
| WO-2008040649-A2 | PYRAZINE-2-CARBOXAMIDE DERIVATIVES AS CB2 RECEPTOR MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-04-10 | — | — | WO | disclosed |