Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 7/20 | 0.52 |
| ▸ | CNR2 | P34972 | 3/20 | 0.52 |
| ▸ | CFD | P00746 | 11/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13690554 | 1.00 | CNR1 (0.52) | CNR1CNR2CFDKDM4EHTR3A | |
| SCHEMBL13691045 | 0.92 | CNR1 (0.51) | CNR1CNR2CFDHTR3A | |
| SCHEMBL4047866 | 0.92 | CNR1 (0.51) | CNR1CNR2CFDHTR3A | |
| SCHEMBL13690564 | 0.89 | CNR1 (0.65) | CNR1CNR2CFDKDM4EHTR3A | |
| SCHEMBL4059110 | 0.89 | CNR1 (0.49) | CNR1CNR2CFDKDM4EHTR3A | |
| SCHEMBL13690557 | 0.89 | CNR1 (0.49) | CNR1CNR2CFDKDM4EHTR3A | |
| SCHEMBL13690544 | 0.86 | CNR1 (0.49) | CNR1CNR2CFDKDM4EHTR3A | |
| SCHEMBL4053493 | 0.86 | CNR1 (0.49) | CNR1CNR2CFDKDM4EHTR3A | |
| SCHEMBL4049353 | 0.85 | CNR1 (0.51) | CNR1CNR2CFDHTR3A | |
| SCHEMBL4049580 | 0.85 | CNR1 (0.51) | CNR1CNR2CFDHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |